Glossary

Term · Baby Basics

serious bacterial infection

Also: SBI, serious bacterial illness

A bacterial infection in the blood, urine, or spinal fluid that can be dangerous for a young baby. Doctors test for it when a very young baby has a fever.

In plain words

A serious bacterial infection is a bacterial infection that has spread into the blood, the urinary tract, or the lining of the brain and spinal cord. In a young baby these infections can move quickly, and early signs can be subtle. Fever is often the first sign, and the baby may also be sleepy, feed poorly, or seem unwell. Clinicians use the baby's age, temperature, and exam to decide what testing is needed. Urinary tract infection is the most common of these in young babies with fever, while infection in the blood or is less common but more dangerous. Many fevers in young babies come from viral infections. That is why clinicians test and watch closely rather than assume. Any fever in a young baby is a reason to call the baby's provider.

The deeper version

Serious bacterial infection in early infancy refers to , urinary tract infection, bacterial meningitis, and other invasive bacterial disease. Urinary tract infection is the most frequent in febrile young infants, and bacteremia or meningitis is less common but more serious. Pantell and colleagues (American Academy of Pediatrics clinical practice guideline, 2021) address febrile infants 8 to 60 days old, with risk highest in the youngest. The guideline stratifies risk by age, temperature, laboratory markers, and clinical appearance for infants 8 to 60 days old. Newborns can present with few signs, so the threshold for evaluation is low. Management decisions about testing, observation, and admission are clinical and individualized.

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Sources

  • Pantell RH et al. — Management of fever in infants 8 to 60 days old: clinical practice guideline, American Academy of Pediatrics, 2021

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