Glossary

Term · Baby Basics

phototherapy threshold

Also: bilirubin treatment level, treatment threshold

The bilirubin level, set by hour of life and other factors, at which a baby is offered phototherapy. It is a guideline number, read on a chart by a clinician.

In plain words

A phototherapy threshold is the level at which treatment is offered. It is not one number for every baby. Clinicians read the level on a chart that looks at the baby's age in hours, how early the baby was born, and other risk factors. The chart is in the guideline, so it can change over time. A level near the threshold may lead to a repeat test in a few hours. Your provider will explain where your baby's level falls and what the next step is. Ask what the number means for your baby, and when the next test will be.

The deeper version

thresholds are published as curves plotted against postnatal age in hours, stratified by gestational age and by neurotoxicity risk factors, including isoimmune hemolysis, , sepsis, acidosis, low albumin, and clinical instability (Maisels et al., 2009; Kemper et al., 2022). AAP guidance supports objective bilirubin measurement, by transcutaneous or total serum bilirubin, with plotting against the threshold to determine follow-up timing. Lower thresholds apply in higher-risk infants. Guideline revisions shift the curves, and comparison across time requires attention to the version in use.

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Sources

  • Kemper AR et al. — Clinical Practice Guideline Revision: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation. Pediatrics, 2022
  • Maisels MJ et al. — Hyperbilirubinemia in the newborn infant of 35 or more weeks' gestation: an update with clarifications. Pediatrics, 2009

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