Glossary

Term · Before Pregnancy

ovarian reserve

Also: egg reserve, egg count, AMH

A measure of how many eggs remain in the ovaries. It is estimated with a blood test and an ultrasound count, and it predicts response to fertility treatment more than natural conception.

In plain words

Ovarian reserve describes how many eggs a person still has in her ovaries. It declines with age over a lifetime. It is estimated with a blood test for anti-Müllerian hormone, called AMH, and with an ultrasound count of small follicles. A lower reserve can mean fewer eggs are available for stimulation during fertility treatment. It does not directly show whether a person can conceive naturally. Many people with a lower reserve conceive without help. Ovarian reserve is one part of fertility evaluation. Other tests look at ovulation, the uterus, and the fallopian tubes. Mothers often hear about it when they are planning or considering treatment.

The deeper version

Ovarian reserve is assessed by antral follicle count on and by serum anti-Müllerian hormone, both of which predict ovarian response to stimulation rather than natural . AMH is produced by small growing follicles and is not reliably linked to natural conception, though it correlates with reserve across ages. Age remains the strongest determinant of oocyte number and quality. Diminished ovarian reserve is a diagnosis based on these markers and ovarian response in treatment cycles, and the ASRM (2015) guidance cautions against using a single marker to counsel on natural conception. Evidence on outcomes in women with low reserve is largely from assisted reproduction cohorts.

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Sources

  • American Society for Reproductive Medicine — Testing and interpreting measures of ovarian reserve: a committee opinion, 2015
  • Practice Committee of the American Society for Reproductive Medicine — Diagnosis and treatment of infertility: a committee opinion, 2015

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