Glossary

Term · Pregnancy: Your Body

Group B strep

Also: strep B, GBS test

Another name for group B streptococcus, a common bacterium that can pass to a baby during birth. See group B streptococcus.

In plain words

Group B strep is a common bacterium. It lives in the gut and lower genital tract of many adults, and most people carry it without any symptoms. It is the same organism as , the clinical name. A swab in late pregnancy checks for it. If a person carries it, the bacterium can reach the baby during labor or when the water breaks. Most babies who are exposed stay well. A small number develop serious infection in the first days of life. Clinicians may give for people who test positive or who have certain risk factors. A positive test is a reason for a plan, not a sign that anyone did something wrong.

The deeper version

Streptococcus agalactiae, group B streptococcus, colonizes the gastrointestinal and lower genital tract in roughly 10 to 30 percent of pregnant women. Intrapartum transmission is the main route to early-onset neonatal disease. Screening at 36 to 37 weeks by vaginal-rectal culture, or a risk-based approach, is described in CDC guidance (Verani and colleagues, MMWR, 2010) and in ACOG Committee Opinion 797 (2020). Intrapartum antibiotic prophylaxis is standard for carriers. For people not screened, decisions depend on risk factors, including , rupture of membranes lasting 18 hours or more, and intrapartum fever. Early-onset disease declined substantially after screening and prophylaxis were introduced. The debate concerns universal versus risk-based screening, the logistics of intrapartum treatment, and antibiotic resistance.

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Sources

  • Verani JR, McGee L, Schrag SJ (CDC) — Prevention of perinatal group B streptococcal disease: revised guidelines from CDC, 2010. MMWR Recommendations and Reports, 2010
  • American College of Obstetricians and Gynecologists — Committee Opinion 797: Prevention of group B streptococcal early-onset disease in newborns (2020)

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